Familial Mediterranean fever: diagnosis and treatment

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Familial Mediterranean fever; diagnosis, treatment, and complications

Introduction Mediterranean fever is an autosomal recessive disease. Its features are intermittent attacks of painful inflammation, abdominal pain, fever, and arthritis. Full identification of the disease has been possible in the last 50 years. It is seen in Turkish, Armenian, Jewish (Arabs, Ashkenazi) and Mediterranean region ethnics. Its attacks take from a few hours to a few days of symptoms ...

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Familial Mediterranean Fever: From Pathogenesis to Treatment

Familial Mediterranean Fever (FMF) is rare autosomal recessive autoinflammatory disorder characterized by periodic bouts of fever, serositis, synovitis, and/or cutaneous inflammation. Painful febrile attacks last 1 to 3 days and can vary in severity. FMF is almost exclusively affecting subjects with Mediterranean origin, especially Armenian, Arab, Jewish, Turkish, North Africans and Arabic desc...

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Genetic Analysis of Southwestern Iranian Patients with Familial Mediterranean Fever

Background: Familial Mediterranean fever (FMF) is an autosomal recessive genetic disorder characterized by recurrent episodes of self-limited fever and serosal tissues inflammation. Methods: To evaluate clinical symptoms and common genetic mutations in southwestern Iranian patients with FMF, 20 unrelated patients were enrolled in this study based on clinical criteria. A panel of 12 common ME...

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Familial Mediterranean Fever

Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by MEditerranean FeVer gene (MEFV) mutations. In Japan, patients with FMF have been previously reported, including a mild or incomplete form. Several factors are presumed to contribute to the variable penetrance and to the phenotypic variability of FMF. We conducted the current study to investigate the correlation of varia...

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ژورنال

عنوان ژورنال: Clinical pharmacology and therapy

سال: 2020

ISSN: 0869-5490

DOI: 10.32756/0869-5490-2020-2-56-67